Your Guide To Adaptogens (2024)

Adaptogens (edible plant extracts) are far from an American health fad. They have been used to treat a variety of ailments over several millennia, particularly in parts of Asia and India.

While they’re experiencing a resurgence in wellness practices today, adaptogenic herbs can only do so much. “There’s a misnomer that adaptogenic treatments are [used] instead of Western medicine,” says Cara Feldman, the administrative director of University of Vermont Integrative Health. “But it’s not alternative medicine. We really emphasize the best of both worlds.”

Learn more about the different types of adaptogens, their benefits and how you can include them in your wellness routine safely and effectively.

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What Are Adaptogens?

Adaptogens are plant substances (often herbs) that have been found to help our bodies manage stress and maintain balance, or homeostasis. In other words, they help us adapt to external stressors. By strengthening our internal systems, adaptogens can promote vitality, stabilize mood and improve performance and focus. They can be consumed as supplement capsules, teas or tinctures.

Adaptogens are meant to help our bodies build resilience to stress and mitigate its further affects on the body. They are not a cure, and they may not work in extreme or immediate cases of anxiety or depression. Further, adaptogens work best in addition to a foundation of a balanced diet and adequate hydration.

How Do Adaptogens Work?

Researchers say adaptogenic herbs interact with the hypothalamic-pituitary-adrenal (HPA) axis, which is a complex system of glands, hormones and receptors in the human body. The HPA axis is central to the body’s homeostasis, stress responses and energy metabolism.

When we consume adaptogens, their organic properties and compounds work with the HPA axis to help balance our systems. If there’s too much of one hormone, for instance, the adaptogens help to lower it. On the flip side, if there isn’t enough of a hormone, adaptogens can help replenish its levels.

Studies also suggest adaptogens interact with the immune-neuro-endocrine system, which helps the body regulate its use of energy and maintain strong immune defenses.

It’s important to remember, though, that research on adaptogenic herbs is ongoing.

Popular Adaptogenic Herbs

Adaptogens are generally known for stress relief, but each herb has its own unique properties that make it useful for specific ailments.

For Stress and Anxiety

  • Ashwagandha, also known as Withania somnifera and Indian ginseng, is a shrub that’s often used in Ayurvedic practices (an ancient Hindu system of medicine). Several clinical studies found ashwagandha can help reduce anxiety when compared to a placebo or other treatments—often significantly. Explore Ashwagandha Powder options on Amazon.
  • Tulsi, known as “holy basil” or the “queen of herbs,” is another shrub commonly used in Ayurvedic medicines. Tulsi is known to promote focus and alleviate anxiety. One clinical trial found it significantly diminished generalized anxiety disorder in patients, as well as their associated stress and depression. Explore Tulsi Powder options on Amazon.

For Fatigue

  • Rhodiola, or Rhodiola rosea, can be found in high-altitude climates in Europe, Asia and North America. In two separate preliminary studies, researchers administered Rhodiola to doctors on night duty and students during an exam period. Results suggest Rhodiola can significantly reduce fatigue when compared to placebos. However, more research is still needed. Explore Rhodiola Powder options on Amazon.
  • Ginseng most commonly refers to either American ginseng or Asian ginseng (also known as red or Korean ginseng), and has been used for medicinal purposes for thousands of years in parts of Asia. Both species of ginseng have resulted in significantly reduced fatigue levels among participants across several clinical trials. At least one study of American ginseng also supports its use in reducing cancer-related fatigue, especially in patients receiving cancer treatments. Explore Ginseng Powder options on Amazon.

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For Immune Health

  • Tulsi, in addition to its anti-stress benefits, can also give your immune system a boost by helping regulate its responses. In one study, healthy participants experienced increased production of certain hormones and types of cells central to the immune system after receiving doses of an alcoholic extract of tulsi on empty stomachs.Explore Tulsi Leaves options on Amazon.
  • Reishi mushrooms, scientifically known as Ganoderma lucidum, are a fungus adaptogen. Their immunity-enhancing properties have been observed in several studies testing reishi’s effectiveness in treating cancerous tumors. Reishi mushrooms increased the number of certain white blood cells in cancer patients undergoing chemotherapy and/or radiotherapy; these participants also experienced improved quality of life with this additional treatment. Experts concluded that reishi mushrooms work best in tandem with other cancer treatments and cannot be deemed effective for tumor shrinkage when used alone. Explore Reishi Mushrooms options on Amazon.

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Benefits of Adaptogenic Herbs

Integrative medicine, and adaptogens specifically, can help fill the gaps left by Western medical practices. Adaptogens have thousands of years of historical use to back up their use, as well as increasingly informative modern studies.

“There’s no substitute [for adaptogens] in Western medicine,” says Andrea Fossati, M.D., an integrative healthcare specialist in Vermont. “If I talk to a patient about using an adaptogen, it might be somebody falling through the cracks.”

Adaptogens help the body’s internal systems build resilience for long-term wellness rather than providing a quick fix. For example, you might react to feelings of tiredness or fatigue by reaching for sugar, coffee or other stimulants. While these might help in the short term, they may actually deplete your energy over time. On the other hand, Rhodiola and ginseng can help slowly build up your body’s ability to ward off fatigue.

Potential Risks and Side Effects of Adaptogenic Herbs

Adaptogenic herbs are nontoxic plants with gentle effects. However, some factors should be taken into consideration before you start consuming them.

They may react with other medications.If you’re taking prescribed medication, integrative health experts suggest talking with your doctor or consulting a naturopath or herbalist before adding any adaptogens into your routine. Your adaptogen of choice may react with the effects of your other medications.

They aren’t universally applicable.Don’t take an adaptogen just because your best friend took it—adaptogens can react differently from person to person, so research which one(s) could work best for your health. Further, consult your doctor or a knowledgeable health care professional if you are pregnant, breastfeeding or immunocompromised and considering taking adaptogenic herbs.

They are better in lower doses.Experts recommend ingesting adaptogenic herbs in small doses each day over the course of six to 12 weeks (unless you’re directed otherwise by your doctor). Taking larger doses in a single sitting may result in adverse effects, such as nausea, vomiting, dizziness or headaches.

How to Add Adaptogens to Your Diet Safely

If you make most of your own meals, you can add adaptogens in their raw forms or as powders to your favorite recipes. You can also find adaptogens in the form of teas, tinctures and supplements.

Whichever route you go, always do your research before buying so you know you’re ingesting a safe product. Learn about each brand, such as where they source their herbs, whether they are GMP (good manufacturing practices) certified and if they use third-party testing. ConsumerLab.com can be a great resource of information for a fee, but you can also call a company directly to ask questions. Natural supplement store staff members might also provide helpful information.

Start slowly and stick to one herb at a time instead of trying several all at once. This way you can determine how each one does or doesn’t affect you before deciding whether to try another one.

Remember, adaptogens aren’t meant to be a quick antidote to anxiety or fatigue. Rather, they help your body build resilience over time.

“Adaptogens are meant to be taken consistently for several weeks at a time,” says Dr. Fossati. “They are also meant to be stopped for a week or so, so you can stop and reacclimate.”

Adaptogen Supplements

Supplement capsules may be one of the easiest ways to integrate adaptogens into your diet. However, the dietary supplement industry is not regulated by the Food and Drug Administration (FDA), which means the quality of what you find on shelves can vary dramatically. Some may consist of a mix of several herbs, which may not produce an optimal effect.

When researching supplement companies, also be sure to check for any heavy metals in their products, which you definitely don’t want to ingest. Researchers have found certain dietary supplements contaminated with heavy metals like cadmium, lead and arsenic beyond daily intake recommendations, which can accumulate in the human body to a level of toxic exposure.

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Sources

Zhang H, Abid S, Ahn JC, et al.Characteristics ofPanax ginsengCultivars in Korea and China.Molecules. 2020;25(11):2635.

Panossian AG, Efferth T, Shikov AN, et al.Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases.Med Res Rev. 2021;41(1):630-703.

Definition of Adaptogen by Merriam-Webster. Merriam-Webster. Accessed 5/20/2021.

Ravishankar B, Shukla VJ.Indian systems of medicine: a brief profile.Afr J Tradit Complement Altern Med. 2007;4(3):319-337.

Liao LY, He YF, Li L, Meng H, Dong YM, Yi F, Xiao PG.A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide.Chin Med. 2018;13:57.

Panossian A, Wikman G.Effects of Adaptogens on the Central Nervous System and the Molecular Mechanisms Associated with Their Stress-Protective Activity.Pharmaceuticals (Basel). 2010;3(1):188-224.

Miller WL.The Hypothalamic-Pituitary-Adrenal Axis: A Brief History.Horm Res Paediatr. 2018;89(4):212-223.

Kulkarni SK, Dhir A.Withania somnifera: an Indian ginseng.Prog Neuropsychopharmacol Biol Psychiatry. 2008;32(5):1093-1105.

Lopresti AL, Smith SJ, Malvi H, Kodgule R.An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.Medicine (Baltimore). 2019;98(37):e17186.

Pratte MA, Nanavati KB, Young V, Morley CP.An alternative treatment for anxiety: a systematic review of human trial results reported for the Ayurvedic herb ashwagandha (Withania somnifera).J Altern Complement Med. 2014;20(12):901-908.

Cohen MM.Tulsi – Ocimum sanctum: A herb for all reasons.J Ayurveda Integr Med. 2014;5(4):251-259.

Bhattacharyya D, Sur TK, Jana U, Debnath PK.Controlled programmed trial of Ocimum sanctum leaf on generalized anxiety disorders.Nepal Med Coll J. 2008;10(3):176-179.

Rhodiola. National Center for Complementary and Integrative Health. Accessed 6/5/2021.

Rhodiola rosea in Flora of North America. eFloras. Accessed 6/5/2021.

Darbinyan V, Kteyan A, Panossian A, Gabrielian E, Wikman G, Wagner H.Rhodiola rosea in stress induced fatigue–a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.Phytomedicine. 2000;7(5):365-371.

Spasov AA, Wikman GK, Mandrikov VB, Mironova IA, Neumoin VV.A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.Phytomedicine. 2000;7(2):85-89.

Asian Ginseng. National Center for Complementary and Integrative Health. Accessed 6/6/2021.

So SH, Lee JW, Kim YS, Hyun SH, Han CK.Red ginseng monograph.J Ginseng Res. 2018;42(4):549-561.

Jin TY, Rong PQ, Liang HY, Zhang PP, Zheng GQ, Lin Y.Clinical and Preclinical Systematic Review ofPanax ginsengC. A. Mey and Its Compounds for Fatigue.Front Pharmacol. 2020;11:1031.

Barton DL, Liu H, Dakhil SR, et al.Wisconsin Ginseng (Panax quinquefolius) to improve cancer-related fatigue: a randomized, double-blind trial, N07C2.J Natl Cancer Inst. 2013;105(16):1230-1238.

Mondal S, Varma S, Bamola VD, et al.Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers.J Ethnopharmacol. 2011;136(3):452-456.

Jin X, Ruiz Beguerie J, Sze DM, Chan GC.Ganoderma lucidum (Reishi mushroom) for cancer treatment.Cochrane Database Syst Rev. 2016;4(4):CD007731.

Jairoun AA, Shahwan M, Zyoud SH.Heavy Metal contamination of Dietary Supplements products available in the UAE markets and the associated risk.Scientific Reports.2020;10(18824).

Ashwagandha. Memorial Sloan Kettering Cancer Center. Accessed 6/5/2021.

Ashwagandha. Medline Plus. Accessed 6/5/2021.

Rhodiola. Memorial Sloan Kettering Cancer Center. Accessed 6/5/2021.

American Ginseng. Medline Plus. Accessed 6/6/2021.

NPA GMP Certification Program. Natural Products Association. Accessed 6/6/2021.

Your Guide To Adaptogens (2024)

FAQs

Your Guide To Adaptogens? ›

Adaptogens are well tolerated by adults, but some noted common side effects include: Nausea. Diarrhea. Dry mouth.

What are the negatives of adaptogens? ›

Adaptogens are well tolerated by adults, but some noted common side effects include: Nausea. Diarrhea. Dry mouth.

Which adaptogen is best for me? ›

The best adaptogens for different health needs:
  • Best for hair and nails: Chaga, cordyceps, jiaogulan.
  • Best for stress: Rhodiola, mucuna pruriens, ashwagandha.
  • Best for fatigue: Ginseng, maca.
  • Best for sex drive: Shilajit.
  • Best for brain fog: Holy basil, rhaponticum.
  • Best for immunity: Maca, chaga, turkey tail, ashwagandha.
Jun 16, 2021

What is the most effective way to take adaptogens? ›

Adaptogens are plants and mushrooms that help your body respond to stress, anxiety, fatigue and overall wellbeing. You can take adaptogens by adding them to food or beverages or take them as tinctures.

Who should not take adaptogens? ›

Certain populations that should avoid adaptogen use include: Pregnant and breastfeeding women. Diabetics. People with high or low blood pressure.

What can you not take with ashwagandha? ›

There is evidence that ashwagandha might interact with some medications, including those for diabetes and high blood pressure, medicines that decrease the immune system response (immunosuppressants), sedatives, anti-seizure medications (anticonvulsants), and thyroid hormone medications.

Do adaptogens give you a buzz? ›

Yes, some adaptogens can give you a buzz. These include green tea, holy basil, ginseng, cordyceps mushrooms, Schisandra berries and maca root.

Do adaptogens cause weight gain? ›

Key Takeaways. Adaptogens are compounds found in plants and some fungi that are believed to help your body increase resilience to stress, reduce inflammation, improve metabolism, moderate appetite, and potentially help with weight loss.

What foods are high in adaptogens? ›

Here are some of the more common adaptogens and their potential benefits:
  • Ginseng. A popular herb among tea drinkers, ginseng comes in two forms as an adaptogen: Asian ginseng (Panax ginseng) and American ginseng (Panax quinquefolius). ...
  • Eleuthero. ...
  • Schisandra. ...
  • Ashwagandha. ...
  • Rhodiola. ...
  • Tulsi (Holy basil) ...
  • Astragalus. ...
  • Cordyceps.
Aug 26, 2021

What is the king of the adaptogens? ›

Eleutherococcus senticosus (Siberian ginseng; Eleuthero): Being one of the most prolifically studied botanicals, Eleuthero has often been referred to as a king of the adaptogenic herbs.

Who shouldn't take rhodiola? ›

Rhodiola is not generally recommended because the claimed beneficial effects on health have not been confirmed in high-quality studies in people and do not outweigh the risk of side effects or drug interactions. Pregnant and breastfeeding women, children, and people with autoimmune disorders should avoid rhodiola.

Which adaptogen is best for anxiety? ›

These five adaptogens may give your brain a boost and help you handle stressful situations:
  1. Ashwagandha. This herb is one of the more studied varieties. ...
  2. Rhodiola rosea. ...
  3. Schisandra chinensis. ...
  4. Eleutherococcus senticosus (Siberian ginseng) ...
  5. Holy basil.

How long does it take for adaptogens to kick in? ›

The time it takes to notice the effects of adaptogens can vary depending on the person, the specific adaptogen, and the way it's used. Some people may begin to feel a difference within a few days, while others may not feel the effects for several weeks or months.

Do adaptogens work immediately? ›

Intelligent adaptogens tend to work best when taken for a period of 6 to 8 weeks; if you don't see results immediately, do not lose patience until you've put in the full time. Adaptogens are meant to adapt with our lives.

Do adaptogens increase estrogen? ›

When you take adaptogens, your endocrine system is freed from having to make cortisol and can instead produce more progesterone, estrogen, testosterone and human growth hormone.

Which is the king of adaptogen? ›

Eleuthero, often dubbed the 'King of Adaptogens,' is a powerful herb with a rich history in Traditional Chinese Medicine and Ayurveda.

Which is better Maca or ashwagandha? ›

If you are looking for stress management and hormonal balance, ashwagandha may prove to be your optimal choice. Alternatively, if you seek an energy boost and libido support, maca could be the ideal adaptogen for you.

Is 800mg of ashwagandha too much? ›

Dosing. Ashwagandha has most often been used by adults in doses up to 1000 mg daily, for up to 12 weeks. Speak with a healthcare provider to find out what dose might be best for a specific condition.

Can you overdose on adaptogen? ›

Adaptogens are generally thought to be free of side effects, although it is possible to experience allergic reactions to their components. Some adaptogens are thought to develop side effects if taken for too long or in too high doses, and there are certain instances where adaptogens might not be suitable for you.

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